Yuchao Jiang, Principal Investigator
Assistant Professor, Department of Biostatistics, Gillings School of Global Public Health
Assistant Professor, Department of Genetics, School of Medicine
Member, Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill


The Jiang Lab’s primary research interests lie in statistical modeling, method development and data analysis in genetics and genomics. Our current research is focused on developing statistical methods and computational algorithms to better utilize and analyze different types of next-generation sequencing data under various setting, with application to data from large-scale cohort studies of human health and disease. Special focus is on single-cell genomics, transcriptomics, and epigenomics, cancer genomics, tumor phylogeny, data normalization, copy number variation detection, DNA damage and repair, and circadian rhythm detection.


I obtained my Ph.D. in Genomics and Computational Biology from the University of Pennsylvania in 2017 working with Dr. Nancy R. Zhang (advisor) and Dr. Mingyao Li. I obtained my M.A. in Statistics from the University of Pennsylvania in 2014 and my B.S. from Cornell University in 2012. I started as a tenure-track Assistant Professor of Biostatistics and Genetics at UNC Chapel Hill in 2017.


Jun 2019: Yuchao gave a talk at the ICSA Applied Statistics Symposium.

Mar 2019: Yuchao gave a talk at the National Institute of Environmental Health Sciences (NIEHS) Biostatistics & Computational Biology Branch.

Mar 2019: Destin is published in Bioinformatics! (HTML, GitHub)

Feb 2019: Book chapter on allele-specific gene expression analysis by single-cell RNA-seq is available online in Computational Methods for Single-Cell Data Analysis by Springer, edited by Dr. Guo-Cheng Yuan. (Link)

Feb 2019: Yuchao gave a talk at the Michigan Center for Single-Cell Genomic Data Analytics at the University of Michigan.

Jan 2019: Yuchao gave a talk in the Department of Epidemiology and Biostatistics in the Arnold School of Public Health at the University of South Carolina. (Link)

Jan 2019: Our joint work with Dr. Aziz Sancar on cross-tissue DNA damage and repair is published in Nature Communications. (HTML, pdf)

Jan 2019: The lab received funding from the UNC Computational Medicine Program Pilot Award, in collaboration with Dr. Qing Zhang at UNC Lineberger Cancer Center. (News)

Jan 2019: Our joint work with Dr. Aziz Sancar on damage and repair of ribosomal DNA is published in Journal of Biological Chemistry. (HTML, pdf)

Dec 2018: Yuchao received the IBM Junior Faculty Developmental Award. (News)

Nov 2018: Yuchao gave a talk at the Genetics Colloquium at UNC-CH.

Nov 2018: CODEX2 is now published in Genome Biology. (HTML, GitHub)

Oct 2018: Yuchao gave a talk at AISC 2018. (Link)

Aug 2018: Yuchao gave a talk at JSM 2018. (Link)

Jul 2018: The lab received funding from the Jayne Koskinas Ted Giovanis Foundation for Health and Policy for a multi-PI proposal titled “Single-Cell Dynamics for Precision Medicine in Cancer”, joint with Stephanie Hicks from Johns Hopkins and Sahand Hormoz from Harvard.

Jun 2018: Yuchao was selected to attend the BD2K Innovation Lab on Single Cell Dynamics at Bend, OR. (Link)

Feb 2018: MARATHON is online at Bioinformatics. (HTML, GitHub)

Jan 2018: The lab received the UNC Lineberger Developmental Award. (News)

Dec 2017: Biostatistics Ph.D. candidates Rujin Wang and Meichen Dong joined the lab. Welcome!

Nov 2017: Gene Urrutia joined the lab as a postdoc fellow. Welcome Gene!

Oct 2017: Yuchao gave a talk at the Bioinformatics and Computational Biology Colloquium at UNC-CH.