Yuchao Jiang

Assistant Professor
Department of Biostatistics
Department of Genetics
University of North Carolina at Chapel Hill


PhD, Genomics and Computational Biology, University of Pennsylvania, 2017

MA, Statistics, University of Pennsylvania 2014

BA, magna cum laude, Cornell University 2012


Jiang Y, Oldridge DA, Diskin SJ, Zhang NR. CODEX: a normalization and copy number variation detection method for whole exome sequencing. Nucleic Acids Research, 43 (6), e39-e39, 2015. (link)

Jiang Y, Qiu Y, Minn AJ, Zhang NR. Assessing tumor heterogeneity and tracking longitudinal and spatial clonal evolution by next-generation sequencing. Proceedings of the National Academy of Sciences, 113 (37), E5528-E5537, 2016. (link, news)

Jiang Y, Zhang NR, Li M. SCALE: modeling allele-specific gene expression by single-cell RNA sequencing. Genome Biology, 18 (1), 74, 2017. (link)

Chen H, Jiang Y, Maxwell KN, Nathanson KL, Zhang NR. Allele-specific copy number estimation by whole exome sequencing. Annals of Applied Statistics, 11 (2), 1169-1192, 2017. (link)

Maxwell KN, Wubbenhorst B, Wenz BM, De Sloover D, Pluta J, Emery L, Barrett A, Kraya AA, Anastopoulos IN, Yu S, Jiang Y, Chen H, Zhang NR, Hackman N, D’Andrea K, Daber R, Morrissette JJD, Mitra N, Feldman M, Domchek SM, Nathanson KL. BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers. Nature Communications, 8 (1), 319, 2017. (link)


Instructor: STAT 101, Introductory Business Statistics, Wharton School, University of Pennsylvania, 2016 Summer (syllabus)


CODEX: COpy number Detection by EXome sequencing (BioC, vignettes)

Canopy: Copy number and single nucleotide mutation analysis of tumor phylogeny (GitHub, CRAN, vignettes)

SCALE: Single Cell ALlelic Expression (GitHub, vignettes)

CODEX2: Full-Spectrum Copy Number Variation Detection by High-Throughput DNA Sequencing (GitHub)


Email: yuchaoj at email dot unc dot edu


4115D McGavran-Greenberg Hall, CB #7420, Chapel Hill, NC 27599-7420 (Biostatistics)

5112 Genetic Medicine Building, CB #7264, Chapel Hill, NC 27599-7264 (Genetics)

Phone: (919)843-3656

Fax: (919)966-3804



We have a postdoc position available as soon as possible in the Department of Biostatistics at the University of North Carolina, Chapel Hill. The research domain is in the field of statistical genetics and genomics with a focus on cancer genomics and single-cell genomics. Applicants are expected to have a Ph.D. degree in Biostatistics, Statistics, Computational Biology, or other quantitative field. Stipend is $60,000 plus fringe benefits. Due to Federally-mandated funding restrictions, the post-doctoral trainee MUST be a US citizen or permanent resident. Interested applicants should send their CV to Dr. Jiang (yuchaoj at email.unc.edu).


We have a programmer/bioinformatician position available as soon as possible through the Department of Biostatistics, Department of Genetics, and the Lineberger Comprehensive Cancer Center at the University of North Carolina, Chapel Hill. Qualified applicants should be proficient in R, Perl, shell script (C/C++ is a plus) and be able to run next-generation sequencing analysis software and pipelines in high-performance clusters. Previous experience with analyzing cancer genomics dataset is highly preferred. Salary starts from $60,000 depending on experience. Interested applicants should send their CV to Dr. Jiang (yuchaoj at email.unc.edu).